Principal Medical
Vascular Device Innovation

Vascular devices, rethought.

Clot and embolic protection, dialysis access, and revascularization — engineered around the procedures clinicians perform every day.

Thrombus & Embolic Protection Dialysis Access Vascular Intervention
Where We Focus

Hard problems in vascular medicine.

From the clots and emboli that threaten hospitalized and high-risk patients, to the high-flow burden and access failures of dialysis, Principal Medical takes on vascular problems where today's devices still fall short — and redesigns them around the patient.

01 / Thromboembolism
900K
Americans are affected by venous thromboembolism each year, and pulmonary embolism is a leading cause of preventable hospital death
02 / Critical Care
5M+
ICU admissions each year in the US, where many patients face transient PE risk but cannot safely receive a permanent filter
03 / Dialysis Access
800K
people in the US live with end-stage renal disease, depending on vascular access that must stay open and safe for years
What We Build

Four areas of vascular innovation.

  • Embolic protection — a tethered, fully retrievable IVC filter for temporary PE protection, without the risks of permanent filters.
  • Atraumatic clot removal — thrombectomy designed to clear thrombus while protecting the vein wall and valves.
  • Dialysis access — flow-control grafts and stents, and a closed-system catheter-clearance device.
  • Revascularization — a hemodynamically optimized bypass graft and precision stent-placement technology.

Each program begins with a procedure clinicians know well — and a device that hasn't kept up with it.

Embolic Protection · Access · Revascularization
The Portfolio

Our technologies.

A portfolio spanning embolic protection, thrombectomy, dialysis access, and peripheral revascularization — each in development, each redesigned around the patient.

Flow-control AV graft
Dialysis AccessPatented

Flow-control AV graft

A dialysis-access graft designed to limit excessive continuous access flow — and the cardiac burden that comes with it — while supporting dialysis. A VascX platform.

Flow-control stent
Dialysis AccessPatented

Flow-control stent

An endovascular stent intended to introduce flow control to existing fistulas and grafts, without open surgery. A VascX platform.

AngioShield filter
Embolic ProtectionPatented

AngioShield filter

A tethered, fully retrievable IVC filter for temporary PE protection — designed to avoid the fracture, migration, and non-retrieval risks of permanent filters. For ICU and intraprocedural use.

Catheter clearance device
Dialysis AccessPatented

Catheter clearance

A catheter-clearance platform intended to help restore function to occluded dialysis catheters through a closed, ready-to-use system.

Bypass graft
RevascularizationPatented

Bypass graft

A hemodynamically optimized lower-extremity bypass graft, with return-limb technology designed to maintain outflow in the low-flow conditions where standard grafts fail.

Atraumatic thrombectomy device — braided mesh basket
Clot RemovalPatented

Atraumatic thrombectomy

A mechanical thrombectomy device that captures the clot in a net and removes it whole — designed to spare the vein wall and valves the trauma of conventional techniques.

AngioShield removable IVC filter
Featured · Embolic Protection

AngioShield removable IVC filter

Up to 70% of permanent IVC filters are never retrieved — a leading source of downstream complications. AngioShield is designed for temporary protection: a tethered, single-wire filter that goes in through a 4F sheath and comes out cleanly at the bedside.

  • Fully retrievable — designed to leave nothing behind
  • Strutless, smooth design intended to avoid fracture and perforation
  • Placed through existing central lines, alongside thrombectomy catheters
See the AngioShield filter
About

Built with the clinicians who use them.

Principal Medical develops devices across embolic protection, thrombectomy, dialysis access, and revascularization. Some improve on procedures clinicians perform every day; others are entirely new. Each begins with a practicing vascular specialist and a problem worth solving.

News

From across the portfolio.

Updates from Principal Medical and its programs.

From VascX

VascX flow-control platform highlighted at VASA

Coverage of the VascX flow-control platform, developed by Principal Medical's dialysis-access subsidiary.

Read at vascx.com
Portfolio

A growing portfolio of vascular technologies

Principal Medical continues to develop its portfolio of vascular and dialysis-access technologies across the pipeline.

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Partnering

Open to strategic collaboration

We welcome inquiries from clinicians, partners, and investors interested in the portfolio.

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Explore the Programs

Learn more about the portfolio.

Detail on each technology in the Principal Medical portfolio.

Dialysis Access Flow-control AV graft Embolic Protection AngioShield filter Dialysis Access Catheter clearance Revascularization Bypass graft Clot Removal Atraumatic thrombectomy Dialysis Access Flow-control stent Subsidiary VascX — flow-control platform Company Contact Principal Medical
Contact

Get in touch.

We welcome inquiries from clinicians, researchers, investors, and potential partners interested in the Principal Medical portfolio.