Principal Medical
Vascular Device Innovation

Vascular devices, rethought.

Clot and embolic protection, dialysis access, and revascularization — engineered around the procedures clinicians perform every day.

Thrombus & Embolic Protection Dialysis Access Vascular Intervention
Where We Focus

Hard problems in vascular medicine.

From the clots and emboli that threaten hospitalized and high-risk patients, to the high-flow burden and access failures of dialysis, Principal Medical takes on vascular problems where today's devices still fall short — and redesigns them around the patient.

01 / Thromboembolism
900K
Americans are affected by venous thromboembolism each year, and pulmonary embolism is a leading cause of preventable hospital death
02 / Critical Care
5M+
ICU admissions each year in the US, where many patients face transient PE risk but cannot safely receive a permanent filter
03 / Dialysis Access
800K
people in the US live with end-stage renal disease, depending on vascular access that must stay open and safe for years
What We Build

Four areas of vascular innovation.

  • Embolic protection — a tethered, fully retrievable IVC filter for temporary PE protection, without the risks of permanent filters.
  • Atraumatic clot removal — thrombectomy designed to clear thrombus while protecting the vein wall and valves.
  • Dialysis access — flow-control grafts and stents, and a closed-system catheter-clearance device.
  • Revascularization — a hemodynamically optimized bypass graft and precision stent-placement technology.

Each program begins with a procedure clinicians know well — and a device that hasn't kept up with it.

Embolic Protection · Access · Revascularization
The Portfolio

Our technologies.

A portfolio spanning embolic protection, thrombectomy, dialysis access, and peripheral revascularization — each in development, each redesigned around the patient.

Flow-control AV graft
Dialysis AccessPatented

Flow-control AV graft

A dialysis-access graft designed to limit excessive continuous access flow — and the cardiac burden that comes with it — while supporting dialysis. A VascX platform.

Flow-control stent
Dialysis AccessPatented

Flow-control stent

An endovascular stent intended to introduce flow control to existing fistulas and grafts, without open surgery. A VascX platform.

AngioShield filter
Embolic ProtectionPatented

AngioShield filter

A tethered, fully retrievable IVC filter for temporary PE protection — designed to avoid the fracture, migration, and non-retrieval risks of permanent filters. For ICU and intraprocedural use.

Catheter clearance device
Dialysis AccessPatented

Catheter clearance

A catheter-clearance platform intended to help restore function to occluded dialysis catheters through a closed, ready-to-use system.

Bypass graft
RevascularizationPatented

Bypass graft

A hemodynamically optimized lower-extremity bypass graft, with return-limb technology designed to maintain outflow in the low-flow conditions where standard grafts fail.

Atraumatic thrombectomy device — braided mesh basket
Clot RemovalPatented

Atraumatic thrombectomy

A mechanical thrombectomy device that captures the clot in a net and removes it whole — designed to spare the vein wall and valves the trauma of conventional techniques.

AngioShield removable IVC filter
Featured · Embolic Protection

AngioShield removable IVC filter

Up to 70% of permanent IVC filters are never retrieved — a leading source of downstream complications. AngioShield is designed for temporary protection: a tethered, single-wire filter that goes in through a 4F sheath and comes out cleanly at the bedside.

  • Fully retrievable — designed to leave nothing behind
  • Strutless, smooth design intended to avoid fracture and perforation
  • Placed through existing central lines, alongside thrombectomy catheters
See the AngioShield filter →
About

Built with the clinicians who use them.

Principal Medical develops devices across embolic protection, thrombectomy, dialysis access, and revascularization. Some improve on procedures clinicians perform every day; others are entirely new. Each begins with a practicing vascular specialist and a problem worth solving.

News

From across the portfolio.

Updates from Principal Medical and its programs.

From VascX

VascX flow-control platform highlighted at VASA

Coverage of the VascX flow-control platform, developed by Principal Medical's dialysis-access subsidiary.

Read at vascx.com →
Portfolio

A growing portfolio of vascular technologies

Principal Medical continues to develop its portfolio of vascular and dialysis-access technologies across the pipeline.

Get in touch →
Partnering

Open to strategic collaboration

We welcome inquiries from clinicians, partners, and investors interested in the portfolio.

Get in touch →
Explore the Programs

Learn more about the portfolio.

Detail on each technology in the Principal Medical portfolio.

Dialysis Access Flow-control AV graft → Embolic Protection AngioShield filter → Dialysis Access Catheter clearance → Revascularization Bypass graft → Clot Removal Atraumatic thrombectomy → Dialysis Access Flow-control stent → Subsidiary VascX — flow-control platform → Company Contact Principal Medical →
Contact

Get in touch.

We welcome inquiries from clinicians, researchers, investors, and potential partners interested in the Principal Medical portfolio.